Winter 2022/2023 Vol. 12 Issue 04
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From the Editor-in-Chief
Taking Aim at CancerTherapeutic antibodies carry ‘payloads’ to destroy cancer cells.
by William G. Nelson, MD, PhD
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Your Cancer Guide
Finding Light in Winter’s DarknessColder temperatures, gray skies and shorter days can dampen the spirits, which can heighten sadness associated with cancer treatment.
by Hester Hill Schnipper
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Caregiving With Confidence
Creating Calm in ChaosA prepacked bag of essential and not-so-essential items can provide structure and comfort to people with cancer during treatment.
by K.J. Bannan
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Policy Matters
Stemming the E-Cigarette EpidemicAn updated AACR-ASCO joint statement recommends steps for policymakers to lower e-cigarette use among youth and young adults.
by Roy S. Herbst, MD, PhD
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Cervical Cancer: A Global ChallengeLow- and middle-income countries make inroads against a preventable and treatable cancer.
by Erin O’Donnell
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Mysterious MicrobesScientists look to decode the role of intestinal bacteria in our responses to immunotherapy.
by Natalie Slivinski
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An Ongoing DiscussionPhysicians are often hesitant to bring up end-of-life care discussions with their patients. People being treated for cancer may need to frame questions to determine their own goals of care.
by Cameron Walker
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Survivor Profile
Rising to the ChallengeJames R. Scott uses his experiences with bladder cancer to be a light for others.
by Lindsey Konkel Neabore
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Q&A
The FDA’s Risk-Benefit FrameworkUsing the withdrawal of Avastin’s approval for breast cancer as a case study, Mikkael A. Sekeres’ new book analyzes the U.S. drug approval process.
by Marci A. Landsmann
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Get Involved
Healing Takes FlightAlicia and Esther Tambe honor their sister’s memory by providing travel experiences to Black women diagnosed with breast cancer.
by Thomas Celona
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Facts and Stats
Setting the StageUnderstanding your cancer’s stage is important for determining your prognosis and treatment options. Here’s what the different stages mean.
by Thomas Celona
A new treatment for people with hormone receptor-positive, HER2-negative disease blocks multiple proteins in a key pathway for treatment resistance.
by Ashley P. Taylor
Amanda Peet Discusses Her Lobular Breast Cancer DiagnosisThe ‘Your Friends & Neighbors’ actress explains how her diagnosis challenged many of her assumptions about breast cancer.
by Darlene Dobkowski
Why I Participated in a Clinical TrialWhen doctors told Yvonne McLean Florence she was eligible to participate in a research trial testing an experimental drug, she joined. She wants more people to have the same opportunity.
by Yvonne McLean Florence
Targeted Therapy Improves Pancreatic Cancer SurvivalA recently approved drug that targets RAS proteins meaningfully improves outcomes for people with this difficult-to-treat cancer.
by Sandra Gordon
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AACR OMB Statement and Call to ActionThe AACR is deeply concerned that proposed OMB regulations would disrupt federal research grant giving, severely weakening a program that has supported American medical innovation for decades.
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AACR Cancer Disparities Progress ReportThe AACR Cancer Disparities Progress Report 2026 highlights recent progress in reducing cancer disparities and emphasizes the continued need for transformative research.
Cancer Research at a Crossroads
