Treatment
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From the Editor-in-Chief
Why Do Targeted Therapies Stop Working?Researchers seek to understand why cancers stop responding to targeted treatments even after initially dramatic responses.
by William G. Nelson, MD, PhD, DSc
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Forward Look
Boosting Chemotherapy’s EffectivenessTargeted treatment that blocks glucocorticoid receptors appears to disrupt signaling that helps ovarian cancer cells withstand chemotherapy.
by Cameron Walker
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Forward Look
Chemotherapy at HomeA pilot program shows some people with cancer may safely receive chemotherapy at home.
by Laura Gesualdi Gilmore
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Forward Look
Hormone Therapy After Prostate Cancer SurgeryStudy shows that adding hormone therapy to postoperative radiation did not improve overall survival in men with low PSA levels.
by Ashley P. Taylor
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The Expanding Role of ADCs
As some antibody-drug conjugates move into first-line and early-stage treatment, researchers seek new targets, payloads and combinations to reach more types of cancer.
by Kendall K. Morgan
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Choosing Your Next Move
CAR T-cell therapies and bispecific antibodies offer options for people with relapsed or refractory multiple myeloma.
by Jo Cavallo
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Sound Advice
What can people with cancer expect during their first chemotherapy appointment?An oncology nurse offers advice for people about to begin chemotherapy, addressing how long visits will take and what to bring with them.
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Targeted Therapy Improves Pancreatic Cancer Survival
A recently approved drug that targets RAS proteins meaningfully improves outcomes for people with this difficult-to-treat cancer.
by Sandra Gordon
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From the Editor-in-Chief
Keeping Score: Cancer Incidence, Mortality and SurvivalShifting federal priorities threaten to undermine cancer mortality and survival gains.
by William G. Nelson, MD, PhD, DSc
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Forward Look
A Gentler Conditioning Regimen for LeukemiaChildren and young adults with no evidence of acute lymphoblastic leukemia after chemotherapy may be able to avoid radiation prior to stem cell transplantation.
by Lindsey Leake
