Winter 2025/2026 Vol. 15 Issue 04
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From the Editor-in-Chief
Adjuvant Therapy: How Much Do Patients Really Need?Sensitive tests help guide treatment decisions.
by William G. Nelson, MD, PhD
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Your Cancer Guide
The Downside of Too Much UpsideDon’t let toxic positivity get in the way of sharing your true feelings about cancer.
by Hester Hill Schnipper
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Caregiving With Confidence
Keeping Stress at BayCaregiving stress may feel inescapable, but several habits can help put overwhelm in check.
by K.J. Bannan
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Policy, Patients & Progress
Prioritizing the Needs of Children With CancerAACR Pediatric Cancer Progress Report 2025 highlights treatment advances and prompts policymakers to keep the momentum going.
by David Zahavi, PhD
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Cancer’s Financial Impact on Young AdultsPeople younger than 40 who come out on the other side of a cancer diagnosis often face a new uncertainty: medical bills and collection calls.
by Charlotte Huff
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The Case for WaitingWith new first-line combination treatments offering deep remissions in multiple myeloma, some people can choose to delay stem cell transplants.
by Sonya Collins
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Rethinking Brain MetastasesWith the option for targeted treatment and radiation, more people with stage IV cancer are being spared from whole-brain radiation.
by Kendall K. Morgan
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Survivor Profile
A Newfound PurposeRectal cancer survivor Manju George draws on her scientific training to help people with colorectal cancer understand their care options.
by Beth Fand Incollingo
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Q&A
Caring for the Whole PersonOncologist Fazlur Rahman recounts how the challenges of life in a rural area can shape a patient’s cancer care.
by Thomas Celona
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Get Involved
Cushions of ComfortAva Clay sews pillows that help ease pain experienced by people with a chemotherapy port.
by Thomas Celona
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Facts and Stats
Alcohol’s Link to CancerDeaths from alcohol-related cancers have nearly doubled in recent decades.
by Thomas Celona
The ‘Your Friends & Neighbors’ actress explains how her diagnosis challenged many of her assumptions about breast cancer.
by Darlene Dobkowski
Why I Participated in a Clinical TrialWhen doctors told Yvonne McLean Florence she was eligible to participate in a research trial testing an experimental drug, she joined. She wants more people to have the same opportunity.
by Yvonne McLean Florence
Targeted Therapy Improves Pancreatic Cancer SurvivalA recently approved drug that targets RAS proteins meaningfully improves outcomes for people with this difficult-to-treat cancer.
by Sandra Gordon
Bring On the WavesA surfer’s love for the ocean guides her through breast cancer treatment and beyond.
by Cameron Walker
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AACR OMB Statement and Call to ActionThe AACR is deeply concerned that proposed OMB regulations would disrupt federal research grant giving, severely weakening a program that has supported American medical innovation for decades.
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AACR Cancer Disparities Progress ReportThe AACR Cancer Disparities Progress Report 2026 highlights recent progress in reducing cancer disparities and emphasizes the continued need for transformative research.
Cancer Research at a Crossroads
