Researchers Discover How Obesity Can Help Ovarian Cancer Spread
In the U.S., ovarian cancer is the fifth-leading cause of cancer death in women. Previous studies have found an association between obesity and ovarian cancer incidence and survival. Using mouse models, researchers demonstrated that as body fat increases, it becomes easier for metastasizing ovarian cancer cells to attach to the cells that cover nearby organs, where they proliferate and form new tumors. This finding supports the epidemiological research linking obesity and ovarian cancer.
Study Identifies Targetable Mutations in Younger Lung Cancer Patients
A study of 2,237 non–small cell lung cancer (NSCLC) patients found 712, or 32 percent, had a tumor with a mutation for which an approved targeted therapy exists or that studies suggest is likely to respond to a targeted therapy. Significantly, patients diagnosed at age 50 or younger had a 59 percent increased likelihood of having a targetable mutation. These results suggest NSCLC in younger people may differ from that in older adults and be more likely to respond to a targeted therapy.
CDC Reports E-Cigarette Ads Reach Millions of Young People
Using data from the 2014 National Youth Tobacco Survey, a new report from the U.S. Centers for Disease Control and Prevention (CDC) reveals about seven in 10 middle school and high school students—about 18 million youth—see e-cigarette advertising. During 2014, about 2.4 million middle school and high school students reported that they had used an e-cigarette within the past 30 days. That year, e-cigarette companies spent $115 million on advertising, up from $6.4 million in 2011.
Review Confirms Link Between Breast and Thyroid Cancer
A meta-analysis of previous studies that included a total of 956,672 breast cancer patients and 44,879 thyroid cancer patients confirmed that breast cancer rates are higher than would be expected in women who have had thyroid cancer, and rates of thyroid cancer are increased in women who have had breast cancer. It’s not clear what is causing the increased risk, but potential explanations include increased attention to screening among cancer survivors, common risk factors and genetics.
New Study Assesses Risk of Heart Disease Among Cancer Survivors
A study of more than 36,000 cancer patients found survivors of multiple myeloma, non-Hodgkin lymphoma and lung and breast cancer were at greater risk of developing heart disease than patients without cancer. The cancer patients who developed heart disease did not live as long as the cancer patients who did not. The researchers say their findings emphasize the need for doctors to address heart health among cancer patients at high risk of developing heart disease.
Study Finds Patient Navigators Improve Satisfaction With Cancer Care
Patient navigators are used to help ensure that timely, high-quality care is provided to underserved communities. A study of 1,345 patients who were assigned a patient navigator after an abnormal cancer screening test or a cancer diagnosis found that patients’ satisfaction with their navigator was significantly associated with their overall satisfaction with their cancer care. The researchers conclude more research should focus on identifying ways to improve patient-navigator programs.
Learn more in the online first Feb. 5, 2016, Cancer
Disparities Seen in Survival Rates Among Adolescents and Young Adults With Hodgkin Lymphoma
Using data collected over a 24-year period from the California Cancer Registry on Hodgkin lymphoma diagnoses in individuals aged 15 to 39, researchers found survival rates differed according to socioeconomic status and race. Black patients were 68 percent more likely to die than non-Hispanic white patients, and Hispanic patients were 58 percent more likely to die. In addition, patients were twice as likely to die if they had public health insurance or were uninsured, regardless of stage at diagnosis.